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We have further shown that resistance-modulating compounds, such as chlorpromazine, interact with haem and efficiently inhibit its degradation.
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Furthermore, both lysosome inhibitors markedly induced down-regulation of Cbl expression in a dose-dependent manner ().
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Amount of drug present in milk does not appear to be harmful to nursing infants, but is insufficient to provide adequate protection against malaria in these infants.
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Antibiotic: A drug that kills or slows the growth of bacteria.
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PHC workers will see more cases of malaria than any other childhood disease; hence malaria case management provides an appropriate clinical condition to measure the effect of supportive supervision of PHC workers.
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An additive effect between azithromycin and chloroquine has been shown in sensitivity testing conducted over a 48-hour period.
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The combination of azithromycin and chloroquine is a potential alternative to SP for IPTp.
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In ACT cells, treatment with sublethal dose of ETO led to the accumulation of LC3 puncta as shown by immune-fluorescence staining (), and this was further confirmed by the increase of LC3-II in the ETO-treated lysate (), thus, ETO treatment indeed induced autophagy.
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Extracts of ETO-treated Y1 cell lysates are analyzed by immunoblotting with antibodies against LC3, γ-H2AX and GAPDH.
The study was conducted in the rural part of the research zone of the Centre de Recherche en Santé de Nouna (CRSN), in Nouna Health District, north-western Burkina Faso.
One question that is still outstanding is the implication that this study was conducted at Ndirande Health Center, on the outskirts of Blantyre.
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Viable parasites were observed in one of four drug-pressured flasks at 42 days, whereas none had emerged within the remaining flasks by 60 days.
When fully prepared, remove the infected specimen from the aquarium and over an empty pail, use a soft brush and the prepared liter solution to remove as much brown jelly as possible.
For AZD6738 treatment, log dose response curves are generated in GraphPad Prism 6 by nonlinear regression (log(inhibitor) vs.
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Untreated the condition gradually resolves over a few days.
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We have seen no problems with its intermittent use for long periods, or with regular use for up to twelve weeks.
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Treatment for extreme (Grade V) may require amputation or euthanasia as the bacteria will actually eat the bone.
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