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In contrast, homologous blood is possible to detect because of the presence of mismatched RBC blood group antigens.

In spite of these observations, the therapeutic goal of reducing the blood pressure to target, regardless of agent used, should not be sacrificed.

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Some side effects may occur that usually do not need medical attention.

Investigator-reported events were independently adjudicated by the clinical committee reviewing end points at the Duke Clinical Research Institute (DCRI), whose members were unaware of patients' study-group assignments.

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Medication Guide and Patient Instructions for Use and should be informed that the Medication Guide is not a disclosure of all possible side effects.

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Since we prespecified the censoring of data on patients at the time of the initiation of renal replacement therapy, no further data were collected; there is a possibility of bias if the rates of renal replacement therapy differed between the two groups.

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